Artificial intelligence (AI) is rapidly transforming the landscape of cardiovascular disease (CVD) diagnosis and treatment, as underscored by a comprehensive study analyzing the academic output in this field. With cardiovascular disease identified as one of the leading causes of death globally, this increase in AI research is particularly timely. The study tracks the evolution of AI applications in CVD from 1987 to March 2025, revealing a surge in publications from a mere 1,738 articles in recent years, predominantly following 2018.
The study highlights the United States, China, and India as the leading contributors to this body of research, with the U.S. leading not just in quantity but also in citation frequency and international collaborations. Institutions such as Harvard Medical School and Mayo Clinic are at the forefront, with Harvard publishing 43 articles and Mayo Clinic receiving over 1,200 citations, marking significant scholarly contributions in the integration of AI within cardiovascular care.
Using advanced bibliometric software such as CiteSpace and VOSviewer, researchers conducted a detailed analysis of the data, revealing key trends and emerging hotspots in AI-related cardiovascular studies. The findings indicate that AI methodologies are increasingly being utilized for diagnosis, classification, and risk prediction in cardiovascular diseases. This trend aligns with the broader acceptance of AI technologies within the healthcare sector, as highlighted by the American Heart Association’s advocacy for AI applications in medicine.
The analysis identifies four main research hotspots: AI-assisted disease diagnosis, emerging biomarkers, AI system design, and AI-assisted disease classification. Machine learning and deep learning techniques are being leveraged to improve diagnostic accuracy and patient stratification, particularly in conditions such as coronary heart disease and arrhythmias. Keywords such as “machine learning,” “deep learning,” and “coronary heart disease” frequently appear in the literature, underscoring their significance in the ongoing research.
Despite the advancements, the study notes several challenges that remain. Data quality and privacy issues pose significant barriers to the implementation of AI in clinical settings. The need for standardized data formats is critical for ensuring accuracy across diverse healthcare systems. Additionally, the interpretability of AI models remains a concern; healthcare practitioners require understanding behind AI-driven decisions to trust their outcomes in patient care.
The research also brings forth the potential for AI to facilitate precise screening and risk prediction. The integration of multimodal data—including imaging, genetic information, and electronic health records—could enhance the accuracy of AI models, leading to better patient outcomes. As AI technology continues to evolve, the focus will likely shift towards developing more sophisticated algorithms that can adapt to the complexities of cardiovascular diseases.
Looking ahead, the role of AI in cardiovascular medicine is expected to expand significantly. The ongoing development of more accurate, interpretable, and user-friendly AI tools will likely drive future innovations in CVD diagnostics and treatment. By fostering collaboration among institutions and countries, researchers aim to overcome current challenges and unlock the full potential of AI, ultimately contributing to improved clinical outcomes for patients with cardiovascular conditions.
See also
IIT Delhi’s AILA AI Runs Complex Lab Experiments Independently, Reducing Time by 90%
AI Study Maps 100 Years of Aging Research, Reveals Key Trends and Gaps
Cornell Study Reveals AI Boosts Paper Output by 50% but Undermines Quality
HCLTech Joins Microsoft Discovery to Boost Agentic AI in Scientific Research


















































